What is it?
Highly sensitive real time PCR kit
This highly sensitive assay enables oncology researchers and practitioners to identify 29 mutations in exons 18, 19, 20 and 21 and develop beneficial therapy for cancer patients.
The epidermal growth factor receptor (EGFR) pathway is implicated in various types of cancer.
Patients with EGFR mutations are resistant to EGFR tyrosine kinase inhibitor therapy.
The presence of EGFR mutations have diagnostic significance because mutation tests helps identify more effective therapy for some patients.
DiagCor’s fast and cost-effective EGFR real time PCR kit provides a highly sensitive molecular technique to detect as low as 1% of mutant molecules present in high background of normal DNA.
Who is it for?
This kit is especially valuable to oncology practitioners and researchers concerned in identifying and treating various cancers.
The GenoQuest EGFR real time PCR kit is also useful to oncology researchers.
Why is it different?
This highly sensitive kit allows selective site-specific detection of mutant DNA.
It can detect less than 1% mutant sequence copies against a background of 99% wild-type DNA.
The ready-to-use reagent is compatible with various real time PCR machines and delivers results 2 hours after extraction.
Accurate – Highly sensitive test allows site-specific detection of less than 1% mutant sequence copies in a background of 99% wild-type DNA
Practical – Detects the full range of mutations located on the EGFR gene
Fast – Delivers results approximately 2 hours after extraction, tests up to 8 samples simultaneously
Easy – No post-PCR manipulation required
Cost effective – Lowest overall cost in market
Need to know
This is a consumable assay kit, developed, supplied and supported by DiagCor. It requires a compatible instrument and a meticulous MDx workflow.
What you get
In the box
Service and support
Seven duplex (FAM + Cy5) EGFR mutation assays with internal control for each assay
Real time master mix
DNase free water
The DiagCor support team includes skilled technicians, engineers and scientists
Distributor and end-users receive direct training supported by video conferencing
Standard operation procedures explain test execution step-by-step
Experienced technicians will familiarize users with procedures by guiding them through a series of trial tests
DiagCor provides extensive training to end users and distributors that covers
Correct application of the system, including how to deploy in public health programs for best ROI
Practical lab technician training
Real-Time PCR machine
High speed centrifuge
QIAamp FFPE extraction kit
EGFR mutation (29 mutations)
||24 tests (real time PCR kit)
||EGFR mutation (29 mutations) in exon 18, 19, 20 and 21: S7681, T790M, L858R, L861Q, G719A, G719C, G719S, 19 deletions, 3 insertions
||Human genomic DNA extracted from fresh, frozen or paraffin embedded tissue
||Internal control; NTC control
||Wild-type or mutated EGFR